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1. Overview of Grants
PREPARE aims to bolster research capabilities for infectious disease preparedness through targeted grants. It funds projects in environment, diagnostics, and therapeutics, evaluated by expert panels.
Last updated 23 October 2025
Open Grant Calls
PREPARE’s overall objective is to support and strengthen essential research capabilities, translational platforms, and expertise to develop tools, methods and products that can be tapped on to detect, respond to, and contain future infectious disease threats. To achieve these objectives, and in our effort to integrate complementary, multidisciplinary R&D capabilities across sectors and institutions, PREPARE will launch Open Grant Calls under the following three Co-operatives:
Environmental Transmission & Mitigation
Diagnostics
Vaccines & Therapeutics
PREPARE will fund research projects that are aligned to our strategy and desired outcomes for epidemic preparedness and response, with emphasis on translational and/or productisation outcomes.
All PREPARE grant proposals are subjected to evaluation by PREPARE’s Scientific Review Panel, which comprise international and local experts from academic institutions and industry. The proposals are evaluated based on their scientific merit and alignment to PREPARE’s strategy.
PREPARE Awarded Projects
For more information about the awarded projects, please contact the PREPARE Programme Office at ncid.PREPARE.Grants@nhghealth.com.sg
List of awarded projects
Grant reference number | Institution | Principal investigator | Project title | Status |
|---|---|---|---|---|
PREPARE-SF-2022-001 | A*STAR Infectious Diseases Labs | Lisa Ng | Outbreak response study on Monkeypox | Closed |
PREPARE-SF-2022-002 | National Centre for Infectious Diseases | Ng Oon Tek | Outbreak response study on Monkeypox | Closed |
PREPARE-SF-2023-003 | National Centre for Infectious Diseases | Ng Oon Tek | Metagenomics for emerging infectious disease detection and surveillance | Ongoing |
PREPARE-SF-2023-004 | Oxford University (Mahosot Hospital), Lao PDR | Audrey Dubot-Pérès | A pilot surveillance system for RSV in children presenting to Hospitals in Lao PDR | Ongoing |
PREPARE-SF-2023-005 | National Institute of Public Health (NIPH), Cambodia | Chhorvann Chhea | Genomic Surveillance for Strengthening Public Health Response in Cambodia | Closed |
PREPARE-SF-2023-006 | National Institute of Hygiene and Epidemiology (NIHE), Vietnam | Mai Le | Pathogen Genomic Surveillance and Immunology in Vietnam | Ongoing |
PREPARE-SF-2024-007 | National Centre for Infectious Diseases | Conrad Chan En Zuo | Clinical validation and cost effectiveness study of a self-administered multi-pathogen antigen rapid test (SMART) | Ongoing |
PREPARE-SF-2024-008 | Diagnostics Development Hub | Weng Ruifen | Singleplex H5N1 ART Prototype Development | Closed |
PREPARE-SF-2024-009 | A*STAR Infectious Diseases Labs | Matthew Zirui Tay | Investigations of H5N1 Influenza Virus Environmental Persistence | Closed |
PREPARE-SF-2024-010 | Institute of High Performance Computing, A*STAR | Ooi Chin Chun | Analytical modelling for predicting dispersal trajectories | Closed |
PREPARE-SF-2024-011 | A*STAR Infectious Diseases Labs | Matthew Zirui Tay | Develop environmental (air, fomite, water) sampling and testing protocols in preparation of cases in Singapore & Study effect of environmental conditions | Closed |
PREPARE-SF-2024-012 | National University of Singapore | Tan Chee Wah | Multiplex surrogate virus neutralisation (sVNT) assay development | Ongoing |
PREPARE-SF-2025-013 | Duke-NUS Medical School | Gavin Smith | Assessing the zoonotic risk and pandemic potential of highly pathogenic avian influenza (HPAI) H5N1 viruses | Ongoing |
PREPARE-CT-2024-002 | National Centre for Infectious Diseases | Ng Oon Tek | A Clinically-Oriented Antimicrobial Resistance Surveillance Network for Healthcare-associated infections (ACORN-HAI) | Ongoing |
PREPARE-UKRI-SF-2025-004 | National University of Singapore | Tan Chee Wah | Development and assessment of novel, high-throughput immunological assays to improve surveillance of spillover of viral families of pandemic potential | Ongoing |
PREPARE-UKRI-SF-2025-007 | National Centre for Infectious Diseases | Ng Oon Tek | Studying Hygiene Interventions to reduce Nosocomial Infections in southeast Asian Intensive CareUnits (SHINIA-ICU) | Ongoing |
PREPARE-CS1-2022-001 | Nanyang Technological University | Julien Lescar | Building and validating a modular vaccination platform via multivalent presentation of antigens using protein-based scaffolds | Closed |
PREPARE-CS1-2022-002 | National University of Singapore | Sylvie Alonso | Harnessing the Clec9A targeting strategy to sustain and broaden protective immune responses in SARS-CoV2 mRNA-vaccinated populations | Ongoing |
PREPARE-CS1-2022-003 | Institute of Materials Research and Engineering, A*STAR | Su Xiaodi | Nanomaterial-based infectious airborne virus sensors for on-site environmental surveillance | Closed |
PREPARE-CS1-2022-004 | Institute of High Performance Computing, A*STAR | Ooi Chin Chun | Development of risk assessment model for infectious respiratory diseases considering human mobility | Ongoing |
PREPARE-CS1-2022-005 | Advanced Remanufacturing and Technology Centre, A*STAR | Nicholas Tong | Integrated mastermix and sample preparation automated system | Closed |
PREPARE-CS1-2022-006 | National University of Singapore | Kevin White | RNA-based mucosal platform | Closed |
PREPARE-CS1-2022-007 | Duke-NUS Medical School | Antonio Bertoletti | Development of a rapid assay for the evaluation of pathogen-specific T cells in human samples | Closed |
PREPARE-CS1-2022-008 | Tan Tock Seng Hospital | Kalisvar Marimuthu | Preparedness program for air and environmental sampling for future outbreak from emerging or novel pathogens | Ongoing |
PREPARE-CS1-2023-010 | Diagnostics Development Hub | Ou Chung-Pei | Development of a PCR based Point of Care Testing (POCT) Device | Ongoing |
PREPARE-CS1-2023-011 | National University of Singapore | Tan Chee Wah | Next-generation all-in-one multiplex surrogate assay for viruses with pandemic potential | Ongoing |
PREPARE-CS1-2024-012 | Experimental Drug Development Centre | Kantharaj Ethirajulu | Assessment of 3CL protease inhibitors for broad-spectrum activity to respond to future pandemics caused by coronaviruses | Ongoing |
PREPARE-CS1-2024-013 | A*STAR Infectious Diseases Labs | Guillaume Carissimo | Cell based viral reporters for future pandemic preparedness | Ongoing |
PREPARE-CS1-2024-014 | National University of Singapore | Andy Tay Kah Ping | TOPAD: Tonsil Organoid Platform for Antibody Discovery | Ongoing |
PREPARE-CS1-2024-015 | National University of Singapore | Justin Jang Hann Chu | Augmenting Cardiac Glycosides as Broad-Spectrum Therapeutics for Orthomyxoviruses and Coronaviruses | Closed |
PREPARE-CS1-2025-016 | Experimental Drug Development Centre | Xu Weijun | Computer-aided and Artificial Intelligence-Empowered Drug Discovery of Best-in-Class/Third-Generation H5N1 Neuraminidase Small Molecule Inhibitors | Ongoing |
PREPARE-CS1-2025-017 | Duke-NUS Medical School | Adamberage Ruklanthi de Alwis | Original Antigenic Sin in Humanized Mice: A Platform for Broadly Protective Antibody Discovery Against Pandemic Pathogens | Ongoing |
PREPARE-CS1-Dx-CORE-2025-001A | Institute of Microelectronics, A*STAR | Doris Ng Keh Ting | Photonics-based Rapid Detection with multiple biomarkers for Respiratory Infectious disease screening | Ongoing |
PREPARE-CS1-Dx-CORE-2025-001B | National University of Singapore | Yan Jie | Development of Multiplexed Immunodiagnostic for Respiratory Viral Infections | Ongoing |
PREPARE-CS1-Dx-CORE-2025-001C | National University of Singapore | Tedrick Thomas Salim Lew | Antibody-Free Nanosensors for Accelerated Viral Protein Diagnostics (AsAP) | Ongoing |
PREPARE-CS1-2025-019 | Nanyang Technological University | May O. Lwin | Vaccines and vaccinations: A study of evolving attitudes | Awarded |
PREPARE-CS1-2025-020 | National University of Singapore | Mathews Mathew | IPS-PREPARE Panel Study on Sociobehavioral Influences in Public Health: A Multi- Year, Multi-Method Approach | Awarded |
PREPARE-CS1-2025-021 | Institute of Mental Health | Mythily Subramaniam | Understanding the Needs of Persons with Mental Illness during the COVID-19 Pandemic and Assessing their Preparedness and Willingness for Research Participation during Future Pandemics | Awarded |
PREPARE-CS1-2025-024 | National University of Singapore | Yi Huso | Socio-behavioural Vulnerability in Migrant Workers: A Longitudinal Panel Study for Pandemic Preparedness | Awarded |
PREPARE-OC-VT-2022-001 | A*STAR Infectious Diseases Labs | Matthew Zirui Tay | Development of an ACE2 decoy as a universal anti-coronavirus therapeutic | Ongoing |
PREPARE-OC-VT-2022-008 | National University of Singapore | Herbert Schwarz | Evaluation of CD137 ligand as adjuvant for enhancing vaccine efficacy | Ongoing |
PREPARE-OC-VT-2022-010 | National University of Singapore | Tan Yee Joo | Establishment and use of robust assays for measuring functional antibodies binding to hemagglutinin (HA) and neuraminidase (NA) of multiple subtypes of influenza A virus in serological analysis of vaccinated and infected people in Singapore | Ongoing |
PREPARE-OC-VT-2022-012 | National University of Singapore | Tran Thai | One-stop integrative platform for fast-track screening of species and tissue tropism of unknown respiratory disease threats (Disease X), and for emerging respiratory pathogen surveillance | Ongoing |
PREPARE-OC-VT-2024-002 | Duke-NUS Medical School | Sook Yuin Jessica Ho | Discovery of anti-influenza A therapeutics with a strategy for simultaneous heterosubtypic targeting that hedge against drug resistance | Ongoing |
PREPARE-OC-VT-2024-003 | Nanyang Technological University | Xiao Tianshu | AI-facilitated development of pan-coronavirus fusion inhibitors | Ongoing |
PREPARE-OC-VT-2024-004 | Nanyang Technological University | Luo Dahai | Development of new self-amplifying RNA based mRNA vaccines for epidemic preparedness and response. | Ongoing |
PREPARE-OC-VT-2024-008 | Genome Institute of Singapore, A*STAR | Chew Wei Leong | Broad-spectrum antiviral RNA nucleases | Ongoing |
PREPARE-OC-ETM-Dx-2023-002 | Singapore-MIT Alliance for Research and Technology | Megan McBee | Wastewater-based assay for epidemic surveillance and population serology | Closed |
PREPARE-OC-ETM-Dx-2023-005 | Genome Institute of Singapore, A*STAR | Chew Wei Leong | Viral detection by direct sample application on functionalised solid state nanopores | Closed |
PREPARE-OC-ETM-D-2023-006 | Genome Institute of Singapore, A*STAR | Niranjan Nagarajan | SurVirAR: An end-to-end rapidly deployable on-site platform for sensitive whole-genome surveillance of viruses using Al-based read-until nanopore analytics | Ongoing |
PREPARE-OC-ETM-Dx-2023-010 | Institute of Materials Research and Engineering, A*STAR | Laura Sutarlie | Ultrasensitive nanomaterial-based sensor coupled with multistage filtration Sample treatment for on-site SARS-CoV-2 wastewater surveillance | Closed |
PREPARE-OC-Dx-2024-002 | Nanyang Technological University | Hou Han Wei | ViroArc: Integrated microfluidics for rapid isolation, enrichment and early detection of live viruses from nasopharyngeal swabs | Ongoing |
PREPARE-OC-Dx-2024-004 | Nanyang Technological University | Xueming Dong | An Automated Rapid Structural-Based Epitope Mapping Platform Based on Hydrogen-Deuterium Exchange Mass Spectrometry | Ongoing |
PREPARE-OC-Dx-2024-005 | Institute of Molecular and Cell Biology, A*STAR | Farid Ghadessy | Development of novel robust polymerase enzymes with increased resistance to inhibitors present in clinical samples and higher processivity for rapid pathogen detection | Ongoing |
PREPARE-OC-Dx-2024-008 | National University of Singapore | Hu Chunyi | VirNASTURE: Virus Nucleic Acid on-Site Testing via Ultra-sensitive Nucleases Escalation | Closed |
PREPARE-OC-Dx-2024-009 | National University of Singapore | Lanry Yung Lin Yue | Isothermally Amplified Antibody-Oligo Probes as Ultrasensitive Rapid Protein Test | Ongoing |
PREPARE-OC-Dx-2024-010 | National University of Singapore | Justin Chu Jang Hann | Development of a cell-free influenza virus infectivity assay with portable-biochips (FLUVIABLEBiochips) | Ongoing |
PREPARE-OC-Dx-2024-012 | National University of Singapore | Tan Yee Joo | Establishing an efficient workflow for in vitro selection of synthetic nanobody libraries to identify high affinity binders of influenza A viral proteins so as to accelerate the development of antigen detection assay in the event of a flu pandemic | Ongoing |
PREPARE-OC-Dx-2025-017 | Singapore University of Technology and Design | Ye Ai | Field-deployable quantitative molecular diagnosis by a portable digital polymerase chain reaction (pdPCR) device empowered with integrated optofluidic technology | Ongoing |
PREPARE-OC-VT-2025-001 | Bioinformatics Institute, A*STAR | Fan Hao | FAST-TRACK: FDA-approved Antiviral Screening Through Translational Research Accelerated by Computational Knowledge | Ongoing |
PREPARE-OC-VT-2025-002 | A*STAR Infectious Diseases Labs | Marco Vignuzzi | A self-amplifying RNA vaccine against Henipaviruses | Ongoing |
PREPARE-OC-VT-2025-003 | A*STAR Infectious Diseases Labs | Matthew Zirui Tay | Single-cell sVNT screening platform for rapid discovery of neutralizing monoclonal antibodies | Ongoing |
PREPARE-OC-VT-2025-004 | A*STAR Infectious Diseases Labs | Ning LI | Developing multisulfonated copper iodide clusters as broad-spectrum intranasal prophylaxis and treatment for viral infections with high outbreak potential | Ongoing |
PREPARE-OC-VT-2025-008 | Nanyang Technological University | Nam-Joon Cho | Development of Broad-Spectrum Peptide-Based Antivirals | Ongoing |
PREPARE-OC-VT-2025-011 | Duke-NUS Medical School | Nina Le Bert | Development of a disease-protective vaccine to control zoonotic paramyxovirus infections through the identification of broadly cross-reactive T cell epitopes | Ongoing |
PREPARE-OC-VT-2025-015 | National University of Singapore | Ge Ruowen | ISM1 as a novel host anti-influenza factor | Ongoing |
PREPARE-OC-VT-2025-019 | National University of Singapore | Chen Kaiwen | Targeting and rewiring of host cell death pathways to fight severe viral infection | Awarded |
PREPARE-OC-ETM-2025-001 | Institute of High Performance Computing, A*STAR | Ooi Chin Chun | Development of a Systematic Assessment Framework for Evaluating Air-Purification Interventions in the Real-world (SAFE-AIR): A First Demonstration on Worker Dormitories | Awarded |
PREPARE-OC-ETM-2025-002 | National University of Singapore | Soh Siow Ling | Charged Spray for Rapid and Targeted Clearance of Airborne Virus-loaded Aerosols | Awarded |
PREPARE-OC-ETM-2025-006 | Nanyang Technological University | Li Hongying | AIM-Mitigation: Advanced Integrated Multimodal Mitigation (AIM-Mitigation) Strategies for Reducing Respiratory Disease via Experimental Testing and Data-Assimilated Artificial Intelligence Modelling | Awarded |
Status of Open Grant Calls
List of Open Grant Calls status
Co-operatives | Status | Deadline |
|---|---|---|
Closed | - | |
Closed | - | |
Closed | - |